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Mechanism of action. This approval includes people with compensated liver cirrhosis, liver transplant recipients, HIV HCV coinfected patients, and people on opioid substitution therapy for drug addiction.
If these medicines are used as a method of birth control, another method must be used during treatment with VIEKIRA PAK, and for about 2 weeks after treatment with VIEKIRA PAK ends. There are six major types of HCV genotypes, among which GT1 is most common infection and constitutes 74 of all cases, while GT4 infection accounts for approximately 1.
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A reduction in colchicine dosage or interruption in colchicine is recommended in patients with normal renal or hepatic function. Thirty-five 85 patients received 12-week treatment and six patients received 24-week treatment; 26 63 patients received ribavirin combination.
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EXVIERA must always be administered together with VIEKIRAX. 1 , 2 The availability of VIEKIRAX and EXVIERA in the UK follows the granting of an EU Marketing Authorisation MA from the European Medicines Agency EMA.
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For patients with genotype 1 HCV, including those with compensated cirrhosis, ombitasvir paritaprevir ritonavir is given once daily, along with dasabuvir twice daily, with or without ribavirin twice daily.